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(2023) 189:G4364

Uncoupling electron flow and O2 consumption from ATP production: Under normal circumstances, electron transport, O2 consumption, and ATP synthesis are obligately coupled through the stored proton gradient and will all slow down if the ATP/ADP ratio becomes high

Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin [PMID: 18493620] Laboratory literature summary: Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway

Additionally, it regulates matrix metalloproteinases (MMPs), ensuring balanced degradation of damaged structural proteins alongside newly synthesized matrix assembly