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Cereda et al., 2006
Initial rates were determined by measuring product generation (for ABTS, guaiacol and DMP) or substrate depletion (for p -coumaric acid and sinapic acid)
Serum concentrations of IGF-2 increase during childhood and then level off at ~500 ng/ml, 29 although abnormal IGF-2 concentrations can occur in certain conditions such as IGF-2-producing tumors
Moreover, the crevasse observed in the inactive structure was absent in the active form, because TM7 shifted toward TM6 after agonist binding (Figure 3)
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