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Up to two-thirds of people regain lost weight within a year of stopping semaglutide, largely due to hormonal and metabolic changes rather than willpower alone

Most TEAEs possibly secondary to FSV deficiency were reported as Grade 1 or 2 in intensity, were nonserious, and did not lead to treatment interruption or discontinuation

While this usually subsides, it raises a valid question: Are people losing weight because their metabolism is optimized, or because they feel too sick to eat

Type II Diabetes Patients: NAION risks increased from 1.8% in non-semaglutide users to 8.9% in semaglutide users , representing a 710% increased absolute risk