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Unlike other GHRPs, Ipamorelin does not significantly elevate cortisol, acetylcholine, prolactin, or aldosterone, making it one of the most targeted GH secretagogues studied in laboratory research
However, they commonly cause gut side effects like indigestion, nausea, vomiting and diarrhoea
Morning administration can be useful for individuals with severe sleep apnea or other sleep disorders that prevent meaningful slow-wave sleep, as the nocturnal GH pulse is already disrupted
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