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The main mechanism of SSRIs is to reduce the rate at which neurons in the brain reabsorb a neurotransmitter known as serotonin
Together, these findings necessitate further investigations to ascertain whether coordinated inhibition of NMDA receptors in GLP-1 receptor neurons modulates neuronal activity beyond canonical feeding regions, such as the mesolimbic dopaminergic reward pathway
Future studies should explore depressive symptoms in diabetes patients treated with anti-inflammatory agents, particularly in comorbid populations
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