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Taken together, these data demonstrate a robust antioxidant response following treatment of microglia with high molecular weight aggregates of -synuclein as demonstrated by an increase in ARE-directed hPLAP activity, morphological changes typical of phagocytic and activated microglia and enhanced expression of proinflammatory molecules and antioxidant response enzymes
This stress can harm cells, exacerbating neurodegenerative diseases and underlying many cognitive issues
in Venoms to drugs: venom as a source for the development of human therapeutics (ed
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