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GLP-1R agonists (e.g., exendin-4 and liraglutide) reduce APP expression and processing in the brains of AD model mice through the activation of GLP-1R, decrease A protein production and plaque aggregation, and thus improve their spatial memory capacity (McClean et al., 2015
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Combining these two agents has opened new avenues for more comprehensive metabolic control, potentially improving weight loss outcomes and glycemic management beyond what either drug can achieve alone
The real kicker is whats not in Xeomin
adding semaglutide does not change this restriction
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