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As we mentioned earlier, GPX7 does not contain domains bound to GSH, so it cannot participate in redox reactions with GSH as a substrate like other GPX family members
Hiramatsu A, Aikata H, Uchikawa S, Ohya K, Kodama K, Nishida Y, Daijo K, Osawa M, Teraoka Y, Honda F, et al
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Assessing whether ferroptosis and its related molecules play essential roles in infertility, metabolic abnormalities, and other aspects of clinical PCOS and whether the administration of antioxidants can prevent ferroptosis, lipid peroxidation, and adverse maternal and fetal outcomes caused by maternal hyperandrogenemia and IR will provide insights and directions for future clinical diagnosis and treatment
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