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At present, the primary approach to treat patients with CCA remains rooted in surgical interventions, and the prognosis for patients ineligible for surgery is poor (103)

For example, in the case of ECs, each cell type, either cardiac or vascular, might have a preferential matrix for optimal culturing, and depending on the objective of the study, the microfluidic composition and dynamics must also be adjusted [270]

A product may also be medicinal where it is intended to restore, correct or modify a physiological function through pharmacological, immunological or metabolic action

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