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TRT influences dopamine and serotonin, improving mood and reducing symptoms of depression and anxiety
99% by reverse-phase HPLC, with 99.5% enantiomeric excess of the (R)-isomer confirmed by chiral HPLC
Discontinuation due to adverse events runs approximately 4-7% across studies, which is comparable to other GLP-1 receptor agonists
The IGF-1 response may also be more robust: 20 to 35% above baseline rather than the 15 to 25% typical of sermorelin monotherapy
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