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[8] (Patients in long-term remission should only be considered for therapy on a case-by-case basis in consultation with an oncologist.) Intracranial Lesions: Sermorelin is not recommended for patients whose GH deficiency is caused by an intracranial tumor or lesion
The 5-on/2-off idea borrows from GH-therapy practice, where periodic breaks are used with the aim of limiting receptor down-regulation
Body composition changes during weight reduction with tirzepatide in the SURMOUNT -1 study of adults with obesity or overweight
Additionally, these drugs act on areas of the brain that regulate appetite and food intake, further promoting a reduction in calorie consumption
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