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In addition to investigating the effects of Setmelanotide on body weight and hunger, researchers also examined quality of life (QOL) and depression scores of participants using the disease-specific Impact of Weight on Quality of Life-Lite (IWQOL-Lite) self-report measure for patients 18 years of age, the age-appropriate Pediatric Quality of Life Inventory (PedsQL) for those under 18 years of age, and the Patient Health Questionnaire-9 (PHQ-9)