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Decrease injection frequency or discontinue use
12,13 Furthermore, disrupting TME-derived epigenetic cues, including CAF-derived exosomes and lactate-induced histone lactylation, may help dismantle pro-resistance niches and restore antitumor immunity
In the early stage, known as striae rubrae, they appear as pink to reddish-purple lines with a slightly raised, sometimes itchy texture
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