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A 35-year-old with a BMI of 32 and no other conditions will require different monitoring than a 60-year-old managing both obesity and type 2 diabetes with existing insulin therapy
Only eight of the included studies examined newer GLP-1 medications, and none followed participants for more than 12 months after stopping treatment
Other factors that may increase infection risk in diabetes patients include: Immunosuppressive effects of poorly controlled hyperglycemia Neuropathy leading to reduced sensation and delayed recognition of infections Vascular complications impairing tissue perfusion and immune cell delivery Frequent antibiotic use for other infections, disrupting normal flora Obesity , which is common in type 2 diabetes and creates skin folds prone to moisture and fungal growth Conversely, medications that improve glycemic control, including GLP-1 receptor agonists and tirzepatide, generally reduce infection risk by normalizing the metabolic environment
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