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In addition to these roles, GLP-1R activation has been demonstrated to exert antifibrotic effects on the fibrosis of solid organs, including the heart, liver and kidneys [25]
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Semaglutide works by mimicking a natural hormone (GLP-1) that regulates blood sugar and helps control appetite
Inhibits the effects of acetylcholine mediated by muscarinic receptors expressed on smooth muscle of the urinary bladder, which relaxes the bladder, and produces a antispasmodic effect
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