To better visualize the changes between IC-B and PEC cells in ABMR compared with normal tissue, we assessed the following pathways related to glutathione metabolism, and vitamin A and biosynthetic machinery, based on cells expressing genes related to each significantly altered pathway, alongside average expression ( Supplementary Figures 4C, D )
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Enzymatic activity assay A solution of the TPE-DCV and GSSG mixture (2.0 mL) was placed in a quartz cuvette (final concentration: [TPE-DCV] = 3 M, [GSSG] = 1 mM)