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The most frequently noted adverse effects in user reports are mild digestive disturbances when taken orally and injection site reactions
The need for vitamin B12 is increased by pregnancy and lactation
Older adults, who often suffer from decreased hydrochloric acid in the stomach, and individuals with gastrointestinal (GI) disorders may have lower absorption of B12.2,4 Vitamin B12 deficiency may be characterized by megaloblastic anemia, fatigue, weakness, constipation, loss of appetite, soreness of the mouth or tongue, and weight loss
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