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One important finding highlighting the diagnostic potential of elemental profiling is the ability to discriminate between healthy persons and those with hypothyroidism via abnormalities of trace elements in serum [68]
The 4-phosphopantetheine group serves as the acyl carrier portion (ACP) of several lipid biosynthetic enzymes that includes cytosolic fatty acid synthase and the mitochondrial NDUFAB1 encoded protein (NADH:ubiquinone oxidoreductase subunit AB1) which serves as the ACP in mitochondrial fatty acid synthesis
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doi: 10.1089/ars.2020.8247 25 BousquetJ.CristolJ.-P.CzarlewskiW.AntoJ
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