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Furthermore, we detected the content of malondialdehyde (MDA), a marker of lipid peroxidation, and found that TGF- treatment increased MDA content, which was mitigated in GPX4-OE cells (Sup
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Notably, the azo-containing chemotherapeutic drug procarbazine for the treatment of Hodgkins lymphoma and brain cancers was found to interact through a similar mechanism of action involving the transformation of GSH to GSSG and regeneration of the catalyst through a reaction with O 2 38,39 , providing feasibility of the proposed catalysis
