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A 2021 systematic review of 16 randomized controlled trials and 6,276 participants (Markun and colleagues, Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue, Nutrients, 2021) found that B12 supplementation does not reliably reduce fatigue in people who are not deficient

The following comparison illustrates the practical cost difference for a typical patient on a monthly maintenance schedule: For patients with pernicious anemia or severe malabsorption where injections are clinically necessary, this cost is justified and often covered by insurance

Used as forever therapy, they are something else, and we will get into that on a separate post

I've been using Skin Biology products for over two years for reducing the appearance of my scars and general skin care