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Finally, statistical comparisons between the different treatment regimes were performed using one-way analysis of variance (ANOVA), the KruskalWallis test, and the MannWhitney test, as implemented in the Prism 10 software platform
Semaglutide represents a promising advancement in the realm of obesity therapies
Semaglutide works mostly through the GLP-1 pathway
On the other hand, metformin-treated mice displayed a slight decrease in body weight, fat mass, and circulating glucose, insulin, and leptin levels, which was associated with a modest reduction of HOMA-IR index and a drop in daily food intake (Fig
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