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Ubiquitin-proteasome system enhancement through 41 upregulated genes strengthens cellular quality control, clearing damaged and misfolded proteins
Proc R Soc Lond B
4d), similar to Atg5 deletion
Early degeneration in the nucleus accumbens in the APP/PS1 mouse model is associated with an A-linked increase in membrane excitability in medium spiny neurons and a reduction in glycinergic synaptic transmission, which may link to apathy (Fernndez-Prez et al., 2020)
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