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Maximum weight loss is the primary goal Previous GLP-1 medications caused intolerable nausea You have concurrent type 2 diabetes needing aggressive treatment You have plateaued on Semaglutide and need additional weight loss Insurance covers Zepbound or cost is not a barrier Patients prioritizing maximum weight loss and who tolerate the medication well typically do better with Tirzepatide
Fix: Servers handle modifications constantly
Nausea, diarrhea, vomiting, and reduced appetite tend to peak during the first weeks of treatment and around dose increases
Only statistically significant results are presented in the main text, while non-significant findings are reported in Supplementary information
