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Protective Effect of Glutathione against Oxidative Stress-induced Cytotoxicity in RAW 264.7 Macrophages through Activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 Pathway Sinha, R., et al

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A 2025 study involving Bifidobacterium strains demonstrated that probiotic-driven tryptophan metabolism produces indole derivatives that activate aryl hydrocarbon receptors (AhR), further upregulating proglucagon gene expression and GLP-1 synthesis (438)

Ciclo vicioso energtico: El dficit de GSH agrava el dao oxidativo mitocondrial, lo que a su vez genera ms radicales libres, consumiendo an ms GSH en un bucle perpetuo de agotamiento energtico