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Diabetes is typically a lifelong condition, making it unlikely that a reduction in obesity would rapidly reverse existing conditions
25,26 Effects on Epicardial Adipose Tissue GLP1-RAs decrease the volume of epicardial adipose tissue, which is often elevated in HFpEF and is a source of proinflammatory cytokines and adipokines
This means insulin is released only when blood glucose levels are elevated, reducing the risk of hypoglycaemia compared with some other diabetes medications
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