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The goal is to determine whether B12 deficiency is present, whether it may be contributing to symptoms, and whether oral B12, B12 injections, or another replacement approach may be appropriate
These metabolic actions within the nervous system leading to the generation of ATP that is necessary for a) the synthesis of mitochondrial DNA neurons, b) for the formation of melanin axonal sheath, c) to provide the biochemical components of neurotransmission d) to maintain the constancy of the internal environment neuronal necessary to generate action potentials and allow transmission at synapses (Neurology, 1995, 45: 11-16)
Unlike oral B12 supplements, which must first pass through the digestive system, B12 injections are absorbed directly into the bloodstream, providing a quicker, more efficient boost
Intramuscular injections may be preferred for deeper absorption , while subcutaneous options may offer ease of use in at-home settings when clinically appropriate
