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It reduces the production of reactive oxygen species (ROS) induced by UV, limits collagen degradation and accelerates the repair of DNA damaged by solar radiation

The group of Schulzke an co-workers showed a disturbance of the barrier function which was accompanied by a down-regulation of claudin-1, 3, 5, 7 and 8, and an up-regulation of claudin-2, a pore-forming claudin, together with a re-distribution of claudin-5 and 8 off the tight junction domain of the enterocytes in intestinal biopsies of patients with CD [23]

An estimated 33.0% of American people aged 20 and above are overweight, 35.7% are obese, and 6.3% are severely obese, according to data from the 20092010 National Health and Nutrition Examination Survey (NHANES), which used measured heights and weights (205)