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In CAR-T cells, expression of an inhibitory resistant PGC-1 isoform reinforced mitochondrial biogenesis programs, stabilized oxidative fitness, and supported durable antitumor potency, providing a transcriptional module that cooperates with contact switch reinforcement and mitochondria to lysosome throughput by sustaining mitochondrial replacement over time (191)
Another reason glutathione has been trending: IV iterations, which Pierrel says are not just a fad
Accumulating extra-synaptic glutamate due to the over-activation of microglia promotes aberrant synaptic signaling in PD and other neurodegenerative brain diseases (Iovino et al
Aghili ZS, Magnani M, Ghatrehsamani M, Nourian Dehkordi A, Mirzaei SA, Banitalebi DM
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