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CrAT deficiency leads to accumulating acetyl-CoA, which exerts an allosteric inhibiting effect on pyruvate dehydrogenase (PDH), a rate-limiting enzyme for pyruvate entry into the Krebs cycle

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When deficiency develops, symptoms can include fatigue, weakness, numbness or tingling in the feet or hands, difficulty walking, mood changes such as depression, and problems with memory or concentration. Untreated, severe deficiency can lead to anemia and neurological damage, so medical attention and proper supplementation are essential. Why Choose B12 Injections

These help protect against age-related diseases including cognitive decline and metabolic disorders