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Both serum total cholesterol (TC) and the total triglycerides (TG) in the rodent models showed a significantly high risk of developing DCM when the mice and the rat data were pooled together (TC: SMD 7.38, p = 0.009
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Based on this rationale, the Flow study (1 mg semaglutide vs placebo) was designed and recruitment began in 2019 until May 2021
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