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One of the most striking modern findings came from a Broad Institute analysis using the Connectivity Map database
Cederbaum (2012) The Km of CYP2E1 for alcohol is 10 mM ,10-fold higher than the Km of ADH for ethanol but still within the range of alcohol concentrations seen in social drinking
Its interaction table lists oral contraceptives and hormone therapies as subject to delayed absorption from gastric slowing, with reduced efficacy described as possible rather than certain
But its not always the easiest thing to do
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