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Wang XJ, Ebbert JO, Loftus CG, Rosedahl JK, Philpot LM

This study suggests that LDN may improve quality of life, reduce pain and fatigue, and enhance immune function, indicating potential benefits for supporting healthspan in aging individuals This study highlights how NAD+ levels decline in both mouse and human Alzheimers brain samples, and how boosting NAD+ may prevent and reverse neurodegeneration and cognitive decline

SEP-479 oral small-molecule agonist of the parathyroid hormone 1 receptor (PTH1R) aimed at treating hypoparathyroidism Recent Highlights: In May 2025, Septerna signed an exclusive global collaboration with Novo Nordisk worth up to $2.2B to co-develop oral small molecule GLP-1, GIP, and glucagon receptor agonists