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Retatrutide represents the next generation of incretin-based therapies, building upon the success of medications like semaglutide and tirzepatide that have transformed weight management approaches
At 12.5 mg weekly, this penultimate dose continues the powerful effects
Understanding your genetic context alongside biomarker data and clinical response empowers more precise provider dialogue about maintenance strategy, potential need for dose adjustments, and whether combination approaches or lower-dose protocols might optimize efficacy and tolerability for your unique biology
These include the expression of key antioxidant enzymes such as superoxide dismutases (SOD1, SOD2), catalase (CAT), and glutathione peroxidase (GPx) (Figure 1) (Valle-Prieto and Conget, 2010)
