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The consistent reductions in BMI and body weight across various studies highlight the potential of GLP-1RAs in managing PCOS-related conditions, even in populations where metformin has traditionally been the first-line therapy
Semaglutide has a seven-day half-life, which means it takes approximately four to five weeks to reach steady state at any given dose
These include people who have type 1 diabetes or have had ketoacidosis in the past
4Devasagayam TP, Boloor KK, Ramsarma T
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