In this episode, we break down: What glutathione actually does Why your levels can become depleted over time The everyday habits that place more demand on your body's natural defenses Your body is working around the clock to protect you, even when you don't realize it
Over time, factors like pollution, stress, UV exposure, and aging can deplete natural glutathione levels, leading to hyperpigmentation, dullness, and uneven skin tone
It is susceptible to carboxypeptidase cleavage, light-driven copper photo-oxidation and pH extremes, with an optimum of about 5.0 to 6.5
Substrate profiling gasdermin D-cleaving proteases We applied our substrate profiling method using a positional scanning library based on the GD_M substrate with a few optimizations to the T7 substrate profiling plasmid (Supplementary Fig