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Zhang X, Zheng C, Gao Z, Chen H, Li K, Wang L, et al
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Over-the-counter copper peptide products are typically cosmetic-grade, much lower in concentration, and mass-produced to have a shelf life of about a year
The autophagy adaptor p62/SQSTM1, essential for targeting ubiquitinated substrates to autophagosomes, is mutated in ALS and FTD, where impaired p62 function results in aggregation-prone protein accumulation and neuronal toxicity
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