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In melanoma patients refractory to antiPD-1 therapy, the combination of Talimogene laherparepvec (T-VEC), an oncolytic herpesvirus, with pembrolizumab (NCT04068181) showed enhanced systemic immune activation and tumor response
Because there is no established or approved dose, anyone treating the numbers below as a protocol is extrapolating well past the evidence
It is important to analyze the potential advantages of taking the medicine at different times during the day
If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable
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