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It should also not be used in patients with Leber's disease (an inherited eye disorder) or megaloblastic anemia caused by a lack of vitamin B12, without first ruling out the possibility of pernicious anemia
The 2022 Dimet-Wiley paper in Scientific Reports characterised NNMT inhibition combined with reduced-calorie diet in diet-induced-obesity mouse model systems (PMID 35013352)
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