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Early diagnosis and treatment play an important role in managing diseases and preventing health problems that lead to more severe consequences

doi: 10.1056/NEJMoa1603827 10 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al

GIPRs have been localized to human pancreatic -cells, and intravenous GIP infusion activates GIPR and intracellular signaling in pancreatic -cells, augmenting glucagonotropic effects in hypoglycemic conditions in humans (130)