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Using both pharmacological and genetic approaches, we demonstrated that liraglutide retained antidepressant efficacy in GLP-1R antagonist-Exn9-treated mice or in Glp1r / mice, whereas gut microbiota depletion abolished its effects
The treatment paradigm mirrors how we approach other chronic conditions: you take the medication as long as you need it, potentially for life
3,4 This receptor and its agonists hold significant therapeutic potential, reshaping the treatment approaches for multiple diseases, including diabetes, cardiovascular disorders, and neurodegenerative diseases
When your appetite reduces or even disappears, youre not just eating less food
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