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Weight Loss Results: In a 48-week trial with people who had obesity: 12 mg dose: Average weight loss of 24.2% 8 mg dose: Average weight loss of 17.5% Placebo: Weight loss of 2.1% Let me put that in perspective: If you weigh 250 pounds: 24.2% weight loss = 60 pounds lost And people were still losing weight when the trial ended (no plateau reached yet) How this compares to other medications: Semaglutide (Wegovy): ~15% weight loss Tirzepatide (Zepbound): ~20% weight loss Retatrutide: ~24% weight loss This is the most significant weight loss we've seen with any medication to date
Washout timing depends on the situation There is no single washout rule for every situation
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