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Trends Pharmacol Sci 27:63945, PMID: 17056127 Andreyev AY, Kushnareva YE, Starkov AA (2005) Mitochondrial metabolism of reactive oxygen species
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Taken together, metformin may upregulate PKA signalling to exert its synergistic protective effects with liraglutide in both GLP-1R-dependent and -independent manners in PA-impaired endothelial cells
Individual responses may vary, and weight changes are not guaranteed
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