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Today, some peptides are widely taken as medication: Insulin, for example, is an FDA-approved peptide, as are GLP-1s, the popular weight loss drugs
1 2 US3091569A, Sheffner AL, "Mucolytic-nu-acylated sulfhydryl compositions and process for treating animal mucus", issued 28 May 1963 Archived 6 August 2024 at the Wayback Machine US patent 3091569, Sheffner AL, "Mucolytic- N -acylated sulfhydryl compositions and process for treating animal mucus", published 28 May 1963, issued 28 May 1963, assigned to Mead Johnson & Co and Mead Johnson & Company Archived 30 June 2024 at the Wayback Machine The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023)
However, substantial heterogeneity across the studies indicated considerable uncertainty in this estimate
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