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26,27 Drug Efficacy and Side Effects in Clinical Trials The first GLP-1RA that received FDA approval was put on the market in 2005 under the name exenatide

Injection Site Reactions Between 5% and 10% of people experience injection site reactions like redness, itching, swelling, or small lumps under the skin

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Each successive generation has been associated with greater effects in published clinical data, though it is important to note that direct head-to-head trials between all three compounds have not been conducted

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