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Dosing & Reconstitution Guide Educational guide for reconstitution and weekly dosing Standard / Gradual Approach (3 mL = ~1.67 mg/mL) Route: Subcutaneous injection

Safety data from over 900 clinical trial participants demonstrates that AOD-9604 is remarkably well-tolerated with a side effect profile indistinguishable from placebo in most studies

Mechanistically, the chemical cocktail suppressed SNAI1 expression, which induced mesenchymal to epithelial transition and HNF4 expression, thereby promoting iHep generation (Zhong et al., 2024)

VDNP: Rate of respiration in the presence of an uncoupler (DNP), indicating maximal electron transport capacity