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Thus, the more pronounced effect on Tpx led us to focus subsequent mechanistic investigations on this target
S., Brcic, L., & Sever, M
Daily subcutaneous or intramuscular injection, ~300-500 mcg/day in standard use
When R-spondin 2 was added to explant cultures from wildtype mice, the number of outer hair cells decreased modestly, further indicating that R-spondin 2 has the opposite effect of -catenin activation in the developing cochlea and do not appear to potentiate canonical Wnt signaling to increase the number of hair cells (Jacques et al., 2012
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