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Peptide drug treatment Mice were treated via subcutaneous (s.c.) injection at the indicated doses with either long-acting acyl-GIP (100 nmol kg 1 s.c.), LIRA (100 nmol kg 1 s.c.) or an acylated peptide GIPR antagonist ([N-Ac,L14,R18,E21]hGIP(531)-K11(E-C16)) (1500 nmol kg 1 s.c.)
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Injections create stronger peaks, while patches provide more consistent levels throughout the day
NCT03856047 prespecified antibody occurrence against cagrilintide as a secondary endpoint, and excluded antibody follow-up time from the in-trial period [6]
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