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The HA modification enables CD44-mediated targeting of tumor cells, while the ZIF-8 framework provides pH-responsive drug release within the acidic TME
Zhou, Y., Zhang, Y., Wang, L., & Wang, Y
Advanced Drug Delivery Reviews, 65(1), 3648
4-Hydroxynonenal 4-Hydroxynonenal (4HNE) is a lipoperoxidation-derived aldehyde that can damage proteins and DNA through the generation of covalent adducts and is implicated in the control of cell signaling 13,14
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