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Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain

This is part of why peptide-focused vendors emphasize per-puncture aseptic technique and dedicated needles per draw direction

References 1 AlmutairiM.GopalK.GreenwellA

The effect of long-term oral L-carnitine administration on insulin sensitivity, glucose disposal, plasma concentrations of leptin and acylcarnitines, and urinary acylcarnitine excretion in warmblood horses

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