Zepbound, the obesity-indication version of tirzepatide, added $5.7 billion in H1 2025, a product that was not launched until late 2023 and is now available in a multi-dose KwikPen
Magnesium glycinate doesnt draw water into the large intestine like magnesium oxide, as its bound with two glycine molecules, leaving no room for water to attach, as it would if you took magnesium oxide
Additional monitoring considerations include assessing for symptoms of pancreatitis (severe, persistent abdominal pain), gallbladder disease (right upper quadrant pain, fever), or diabetic retinopathy changes
DPP-4 inhibitors may be preferred for: Patients unable or unwilling to use injectable therapies Elderly individuals where the lower hypoglycaemia risk is particularly valuable Those at high risk of hypoglycaemia from other medications Patients requiring modest glycaemic improvements Individuals where weight neutrality is acceptable or desired Important cautions and contraindications: Do not combine a GLP-1 receptor agonist with a DPP-4 inhibitor